Newcastle's Jonjo Shelvey scores a majestic goal in training
Newcastle are winless after seven Premier League games this season, and Rafa Benitez will know his side have a big opportunity to end their drought this weekend.
The Magpies have played four of last season's top six already in 2018/19, losing 2-1 on every occasion, but Manchester United have endured a nightmare start to the season compared to Newcastle's previous opponents.
Benitez has been criticised for his defensive tactics in recent weeks, and fans will be desperate to see his team try to attack United in their vulnerable state.
Newcastle are boosted by the return of Federico Fernandez and Paul Dummett to ease the defensive crisis that was brewing at St James' Park.
The pair of defenders were ruled out of last weekend's game against Leicester late on, but have both recovered from knocks and go straight into the team.
DeAndre Yedlin was also a doubt for last week, though he did feature and has not shown any ill-effects in the build-up to the United showdown.
Florian Lejeune remains a long-term injury absentee despite his rehabilitation progressing well.
Salomon Rondon is ruled out of the United game with a thigh injury with Joselu set to lead the line once again.
Newcastle team news: How will the Magpies start against Man Utd? (Image: Getty Images/buildlineup.com)
Newcastle team news: Express Sport's predicted XI vs Manchester United (Image: buildlineup.com)
Newcastle team news: Salomon Rondon is ruled out through injury (Image: Getty Images)
Invalid email
We use your sign-up to provide content in ways you've consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. Read our Privacy Policy
The Spanish striker has scored twice this season, both times in August.
Yoshinori Muto is yet to start for the Magpies, with Benitez seemingly reluctant to give his £9.5million summer signing game time despite the lack of goals.
The former Mainz 05 star has made six substitute appearances in the Premier League this season, totalling less than 90 minutes on the field.
Ayoze Perez is likely to start through the middle, with Matt Ritchie and on-loan Chelsea prospect Kenedy on either flank.