The Chilean looks to be vying for a place with on the left wing with Anthony Martial.
Despite limping off against Reading, Sanchez is ready for first-team action but Martial is expected to keep his place after impressing since Solskjaer came in.
He should line up as part of a three-man attack alongside Marcus Rashford and Jesse Lingard.
Rashford has scored three goals and grabbed two assists under Solskjaer and is certain to lead the line, with Romelu Lukaku on the bench once more.
Ole Gunnar Solskjaer has to decide who to select for Manchester United's clash with Tottenham (Image: GETTY)
While the Norwegian has an abundance of options in attack, the same cannot be said at the back.
Chris Smalling is still nursing an injury but should be fit for place on the United bench.
Marcos Rojo is another long-term casualty and he has returned to his homeland to have surgery.
“He’s gone back to Argentina for a while because of his injury,” Solskjaer said.
Paul Pogba is fit for United (Image: GETTY)
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How United could line up against Tottenham (Image: BUILDLINEUP)
“Mentally it was important for him to get away and then come back fresh again.”
Smalling’s fellowcentre-backEric Bailly is still suspended after being shown a straight red card against Bournemouth.
United have lost their last three Premier League away games against Spurs and have only four wins in their last 17 matches in London.
But if Solskjaer can mastermind a rare victory, he will equal Matt Busby’s record of a United manager winning their first five league matches in charge.