The Brazilian could make his second debut for the club against Swansea on Sunday (4pm) after his £30million deadline day transfer from Paris Saint-Germain.
Luiz has trained alongside his team-mates this week in a bid to prove his fitness.
And the centre-back is confident he can adapt to Conte's methods.
He said: "I started playing three at the back with Vitoria in Brazil, but it doesn’t matter where, I want to help and when I am in the team I am there to try to help.
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Gary Cahill, John Terry and David Luiz of Chelsea
"The coach is an amazing coach, he understands a lot of tactical things and I know he chooses every match the best line up, so if he needs to play three, four or two, it doesn’t matter, I am there if he wants me to play.
"In different positions I am available."
And Luiz, 29, is eager reimmerse himself in the Premier League with 'tough' games against the Swans and Liverpool coming up.
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He added: "My first game for Chelsea was Liverpool at home. It is big but they are always tough games here.
"Against Swansea it will not be easy, I played in draws there before, so it is always a tough game.
"Then in the league after Liverpool it is a London derby. They will be tough games.