Rostov will head to Old Trafford next Thursday (8.05pm) for the second leg showdown.
However, they will be without experienced 35-year-old Kalachev after he picked up a suspension.
The Belarus international’s yellow card in the 72nd minute was for hanging out a foot in midfield.
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Jose Mourinho was angry about the state of FC Rostov's pitch before Manchester United's tie
I wanted you to get the yellow card
Jose Mourinho
Following the foul, Kalachev had verbals with Jose Mourinho on the touchline.
And after the final whistle, United’s manager spoke to the Rostov midfielder.
Caught on camera, the Portuguese was seen joking about the incident which resulted in his yellow card and ban for next week.
“I wanted you to get the yellow card,” Mourinho told Kalachev.
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Jose Mourinho was up and down his touchline in Manchester United's 1-1 draw with Rostov
Timofei Kalachev's yellow card has ruled him out of the second leg at Old Trafford against Man Utd
The Manchester United boss’ relief was evident as he was Rostov’s best player on the night.
Kalachev provided the assist for his side’s second-half equaliser, chipping a ball over the top of United’s defence for Bukharov to finish.
And he continued to cause problems in midfield for the Red Devils.
Mourinho can secure Champions League football by lifting the Europa League trophy, and any advantage to help them reach the final will be welcomed by the United manager.